In one study, scientists measured the effect of B6 supplementation on platelet aggregation and cholesterol levels in 24 healthy men. Vitamin B6 may be particularly important. Most notable are antioxidant nutrients flavonoids and other polyphenols enzymes such as nattokinase garlic and vitamin B6. In addition to omega-3 fatty acids, there are a number of supplements that impact platelet aggregation. If you already have cardiovascular disease, elevated CRP levels, or high triglyceride levels, the recommended dosage is 3,000 mg daily. In fact, the beneficial effects of fish oils on platelet aggregation is one of the key reasons why higher levels of EPA and DHA in the diet are associated with a 50 percent reduced risk of stroke and heart attack.įor health maintenance, try a fish oil supplement that provides a daily dose of 1,000 mg combined of EPA and DHA.
Particularly useful for decreasing platelet aggregation are the long-chain omega-3 fatty acids EPA and DHA, found in fish oil. While saturated fats and cholesterol increase platelet aggregation, omega-3s and monounsaturated fats have the opposite effect. The “stickiness” of your platelets is largely determined by the types of fats in your diet and the amount of antioxidants you consume. Once platelets aggregate, they release potent compounds that promote the formation of plaque-or they can form a clot. Any one of these events can result in death.Įxcessive platelet aggregation is part of the process of atherosclerosis, and is an independent risk factor for heart disease and stroke all its own. And if it happens in the lungs, it causes a pulmonary embolism. If it happens in the brain, it can cause a stroke. If it blocks a blood vessel in the heart, it leads to a heart attack (also called a myocardial infarction). The bigger the clot, the bigger-and more important-the vessel it can block. As a result, blood flow to that part of the body stops, and nearby organs or tissue can die. If a piece of the clot breaks off, it will eventually circulate into a vessel that’s too small to allow it to pass. Plaque can also lead to the formation of blood clots-thickened clumps of blood that form when blood platelets collect at the site of blood vessel damage. Normally your arteries are very flexible, like a rubber tube, but plaque causes them to become stiff, and can even block blood flow. One of the primary causes of heart attacks and strokes, atherosclerosis is the hardening of artery walls due to a buildup of plaque.
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